2. Signaling Pathways
  3. GPCR/G Protein
  4. Motilin Receptor
  5. Motilin Receptor Antagonist

Motilin Receptor Antagonist

Motilin Receptor Antagonists (4):

Cat. No. Product Name Effect Purity
  • HY-107642
    MA-2029
    		Antagonist 98.94%
    MA-2029 is a selective, orally active, and competitive motilin receptor antagonist (IC50=4.9 nM). MA-2029 is selective for the motilin receptor over various other receptors and ion channels. MA-2029 may be useful for gastrointestinal disorders associated with disturbed gastrointestinal motility.
  • HY-P1233
    ANQ-11125
    		Antagonist
    ANQ-11125 is a potent and selective antagonist of motilin, with the pKd of 8.24. ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit.
  • HY-P1233A
    ANQ-11125 TFA
    		Antagonist
    ANQ-11125 TFA is a potent and selective antagonist of motilin, with the pKd of 8.24. ANQ-11125 TFA blocks motilide-induced contractions in vitro in the rabbit.
  • HY-171853
    RWJ-68022
    		Antagonist
    RWJ-68022 (Example 9) is a cyclopentene derivative and a motilin receptor antagonist. RWJ-68022 can compete with motilin and erythromycin for the motilin receptor site. RWJ-68022 can be used in the research of gastrointestinal-related diseases.